Elephant's cancer-fighting secret sheds light on preventing human cancer

By Park Sae-jin Posted : October 22, 2015, 16:03 Updated : October 22, 2015, 16:03
Elephants rarely get cancer. Now, scientists know why.

Researchers said they discovered the secret to the world's biggest land animal of their special protection ability.

According to the study in the Journal of the American Medical Association, elephants have 38 additional modified copies of a gene that encodes p53, a compound that suppresses tumor formation. Humans, on the other hand, have only two.

"We think that making more p53 is nature's way of keeping this species alive," said co-senior author Joshua Schiffman, pediatric oncologist of the Huntsman Cancer Institute at the University of Utah School of Medicine.

Elephants also come naturally equipped with a special internal mechanism for killing damaged cells that are at risk for becoming cancerous, researchers said.

Scientists hope that by decoding elephants' cancer-fighting skills, they might gain new insights into how to better prevent human cancer.

By Ruchi Singh
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